TIL-based Therapies Market by Target Indications
Roots Analysis has announced the addition of TIL-based Therapies Market report to its list of offerings.
Cancer is one of the leading
causes of mortality, accounting for 0.6 million deaths in 2019, in the US
alone. The International Agency for Research on Cancer (IARC) states that by
2040, the global burden of cancer is expected to grow to 27.5 million new cases
and 16.3 million cancer deaths annually.[1], [2] Although cancer therapeutics
continue to be one of the most active areas in terms of drug development, there
is still a significant unmet need in this domain. Conventional cancer
treatments, such as chemotherapy, surgery and radiation therapy, have demonstrated
very limited efficacy in late-stage cancers. Specifically, chemotherapy and
radiation therapy are also associated with several side effects. Their
non-specific nature has severe detrimental effects on the patients’ quality of
life.[3]
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Scope of the Report:
The “TIL-based Therapies Market by Target Indications (Melanoma,
Head and Neck Cancer, Breast Cancer, Hepatocellular Cancer, Sarcoma, Chronic
Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, and Cervical Cancer), Key
Players and Key Geographies (North America, Europe and Asia Pacific) – Global
Forecast 2021-2030” report features an extensive study of
the current market landscape and future potential of TIL-based therapies. The
report highlights the efforts of both industry players and academic
organizations in this rapidly evolving segment of the biopharmaceutical industry.
Amongst other elements, the report features the following:
- A
detailed assessment of the current market landscape of TIL-based therapies
with respect to type of developer (industry / non-industry), phase of
development (preclinical, phase I, phase I/II and phase II),
therapeutic area (hematological cancer, solid tumor and others),
popular target indications (melanoma, ovarian cancer, pancreatic
cancer, head and neck cancer, sarcoma, colon cancer, acute myeloid
leukemia, stomach cancer, chronic lymphocytic leukemia, cervical cancer,
breast cancer and others), source of T-cells (autologous and
allogeneic), dose frequency (single dose, multiple dose and split
dose), target patient segment (children, adults and elderly
patients) and type of therapy (monotherapy and combination
therapy). Further, the chapter provides detail on the most active
players (in terms of number of pipeline candidates) engaged in
this domain.
- An
analysis highlighting the key opinion leaders (KOLs) in this domain. It
features a 2×2 matrix assessing the relative experience of KOLs
shortlisted based on their contributions (in terms of involvement in
various clinical studies) in this field, and a schematic world map
representation, indicating the geographical location of eminent scientists
/ researchers engaged in the development of TIL-based therapies.
- Detailed
profiles of therapies being evaluated in clinical stages (phase I/II
or above); each profile features an overview of the therapy, its mechanism
of action, current development status, key clinical trial results, dosage
regimen and manufacturing information.
- An
overview of key therapeutic areas that are being targeted by
TIL-based therapies. It also includes an assessment of the
opportunity (in terms of revenue generation potential from therapy
sales) across oncological disease indications.
- An
analysis of the partnerships that have been established in the recent
past, covering R&D agreements, license agreements (specific to
technology platforms and product candidates), product development and
commercialization agreements, manufacturing agreements, clinical trial
collaborations, product supply management agreements, joint ventures and
others.
- An
analysis of investments that have been made into companies which have
proprietary TIL-based products / technologies. The various type of funding
instances reported in this domain include seed financing, venture capital
financing, capital raised from IPOs and subsequent public offerings,
grants, and debt financing.
- A
case study on manufacturing of cell therapy products, highlighting the key
challenges associated with the production of such therapies. In addition,
it features a detailed list of contract service providers and in-house
manufacturers engaged in this market.
- An
elaborate discussion on various factors that form the basis for the
pricing of cell-based therapies. It features different models / approaches
that a pharmaceutical company may adopt, in order to decide the price of a
TIL-based therapy.
- A
review of the key promotional strategies that have been adopted by
developers of marketed T-cell therapies, namely KYMRIAH® and YESCARTA®.
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Key Questions Answered
- What
are the prevalent R&D trends related to TIL-based therapies?
- Which
are the key therapeutic areas targeted by TIL-based therapies?
- Who
are the leading industry and non-industry players engaged in the
development of TIL-based therapies?
- What
challenges are commonly faced by stakeholders engaged in this domain?
- Who
are the key investors in this domain?
- Who
are the key opinion leaders / experts engaged in this upcoming field of
therapeutics?
- Which
types of partnership models are commonly adopted by industry
stakeholders?
- Which
are the key regions where contract manufacturing support is available for
TIL-based therapies?
- What
are the different types of promotional strategies that are likely to be
adopted for approved / yet to be commercialized TIL-based therapies?
- Which
factors are likely to influence the evolution of this upcoming market?
- How
is the current and future market opportunity likely to be distributed
across key market segments?
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About Roots Analysis
Roots Analysis is one of the
fastest growing market research companies, sharing fresh and independent
perspectives in the bio-pharmaceutical industry. The in-depth research,
analysis and insights are driven by an experienced leadership team which has
gained many years of significant experience in this sector. If you’d like help
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Contact Details
Ben Johnson
+1 (415) 800 3415
ben.johnson@rootsanalysis.com
Roots Analysis
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